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tecan d300e device  (Tecan Systems)


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    Structured Review

    Tecan Systems tecan d300e device
    Tecan D300e Device, supplied by Tecan Systems, used in various techniques. Bioz Stars score: 98/100, based on 915 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tecan+dispenser/D300e+Digital+Dispenser/pm42580486-88-5-5
    Average 98 stars, based on 915 article reviews
    tecan d300e device - by Bioz Stars, 2026-11
    98/100 stars

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    Related Articles

    Concentration Assay:

    Article Title: Biological Activity and Structural Biology of Current KAT6A Inhibitor Chemotypes.
    Article Snippet: Then, 2 μL/well of the 4x concentrated serially diluted compounds were transferred from the intermediate compound plate to duplicate assay plates using the JANUS G3 Automated Workstation Modular Dispense Technology (MDT)-384 Tip Head (PerkinElmer). .. The compound treatment of cells started 1 day after seeding with a final DMSO concentration of 0.1% and was performed by nanodropdispensing using a Tecan Dispenser (D300e). ..

    Article Title: Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing
    Article Snippet: AMD3100, UCUF-728 and SDF-1a (PeproTech; Cranbury, NJ, USA) were dispensed in concentration-response mode using the TECAN D300e digital dispenser into white 384-OptiPlates (Perkin Elmer, Waltham, MA, USA). .. Forskolin at final concentration of 0.5 mM was added to all wells using the TECAN dispenser. .. Ten milliliters of PathHunter CHO-K1 CXCR4 cells (DiscoverX, Fremont, CA, USA) were added to compounds at 3000 cells/well, centrifuged at 1000 rpm for 30 s and incubated for 30 min at room temperature.

    Article Title: Biological Activity and Structural Biology of Current KAT6A Inhibitor Chemotypes
    Article Snippet: After incubation for 7 days at 37 °C at 5% CO 2 , cell plates were equilibrated to room temperature for one hour, CellTiterGlo reagent (Promega) was added and luminescence was measured approximately an hour later using a luminometer (EnVision, PerkinElmer). .. The compound treatment of cells started 1 day after seeding with a final DMSO concentration of 0.1% and was performed by nanodrop-dispensing using a Tecan Dispenser (D300e). ..

    other:

    Article Title: Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting.
    Article Snippet: cDNA was amplified with gene-specific (HK2, FBP1 and PKM) TaqMan probes (Applied Biosystem) using TaqMan Universal Master Mix II (Thermo Fisher Scientific).

    Article Title: Design, Synthesis, and Biological Evaluation of 3,4-Dihydroisoquinolin-1( 2H )-one Derivatives as Protein Arginine Methyltransferase 5 Inhibitors for the Treatment of Non-Hodgkin's Lymphoma.
    Article Snippet: Through catalyzing the transfer of methyl groups onto the guanidinium of arginine, protein arginine methyltransferase 5 (PRMT5) was essential to the cell growth of cancer cells.. By utilizing a scaffold hopping strategy, a novel series of 3,4dihydroisoquinolin-1(2H)-one derivatives were designed and synthesized.. Through a systematic SAR study, D3 demonstrated excellent PRMT5 inhibitory activity, potent antiproliferative activity against Z-138, favorable pharmacokinetic profiles, and low hERG toxicity.

    Inhibition:

    Article Title: Identification and characterization of select oxysterols as ligands for GPR17.
    Article Snippet: Test compounds were added directly to cells using the Tecan D300e Digital Dispenser and allowed to incubate for 45 min at room temperature. .. For inhibition experiments, I-116 was dispensed directly to cells in a concentrationdependent manner using the Tecan dispenser and incubated for 15 min at room temperature before addition of the EC90 of agonists nloaded from https://bpspubs.onlinelibrary.w iley.com /doi/10.1111/bph.15969 by Indian Institute O f T echnology, W iley O nline L ibrary on [31/01/2024]. ..

    Incubation:

    Article Title: Identification and characterization of select oxysterols as ligands for GPR17.
    Article Snippet: Test compounds were added directly to cells using the Tecan D300e Digital Dispenser and allowed to incubate for 45 min at room temperature. .. For inhibition experiments, I-116 was dispensed directly to cells in a concentrationdependent manner using the Tecan dispenser and incubated for 15 min at room temperature before addition of the EC90 of agonists nloaded from https://bpspubs.onlinelibrary.w iley.com /doi/10.1111/bph.15969 by Indian Institute O f T echnology, W iley O nline L ibrary on [31/01/2024]. ..

    Article Title: Development of patient derived organoids for cancer drug screening applications.
    Article Snippet: Cancer is a disease characterised by abnormal cell growth that can invade or spread to other regions of the body.. Organoids are three-dimensional ex vivo tissue cultures made from embryonic stem cells, induced pluripotent stem cells, progenitor cells or tissue that serve as a physiological model for cancer research.. These are designed to recapitulate the in vivo properties of tumours.



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